A general equation including competitive, uncompetitive and noncompetitive inhibition as special cases.
Names: Vmax, Km, Ki, Alpha, Ic
Meanings: Vmax = Maximum enzyme velocity, Km = Michaelis-Menten constant, Ki = Inhibition constant, Alpha = Constant that determines mechanism, Ic = Inhibitor concentration constant
Lower Bounds: Vmax > 0.0, Km > 0.0, Ki > 0.0, Alpha > 0.0
Upper Bounds: none
Note: This fitting function is for global fitting. When using it, Vmax, Km, Ki, and Alpha are shared, while Ic is a fixed constant.
If Alpha=1, the mixed model is same as a noncompetitive inhibition model. If Alpha is very large, the mixed model is similar to a competitive inhibition model. If Alpha is very small, the mixed model is similar to an uncompetitive inhibition model.