Select at least one Y column (or a range from at least one Y column). Ideally, select two Y columns (or a range of two Y columns). If there is an associated X column, X column supplies X values; otherwise, sampling interval of the Y column or row number is used.
Select required data.
Select Plot > Multi-Panel/Axis: Double-Y Column from the main menu.
DblY_Col.OTP (installed in the Origin program folder).
This graph type has one layer only and 2 Y axes with different axis scale, same as the double Y axis Graph. In this graph, all Y column(s) will be plotted as columns, no matter which Y axis they are basing on.