When column format is set to Numeric and Data Type is set to other options e.g. Real(4) instead of the default Double(8), user can assign a custom value as missing value, such as:
wks.col1.missing = -99; //-99 will show as missing value --
wks.col2.missing = 0; //0 will show as missing value --
wks.col1.missing = 0/0 //turn the feature off
This property is saved with the column.