Cell formula would be calculated from time to time in the previous versions, so if the source data is huge, it will be slow. There is a value cache for cell formula though, but it will be cleared after time limit is reached, which is control by @SCNT (time interval as milliseconds, default is 5000). So if your project is slow with cell formula, can set @SCNT to be a huge number to avoid recalucation.

Since Origin 2023, cell formula will keep using cache result until data change, so it will not recalculate frequently. And then if you want to force clear the cache to force cell formula values to update, press F5 to refresh or set @SCNT = -1 to do it.